I am a research group leader working at the interface of chemistry and biology.

About me

My name is Jacek. I’m a scientist and group leader at the Polish Academy of Sciences in Poznań. My group is growing with dynamic opportunities in chemical biology and chemistry, and there are opportunities to join as an assistant professor, post-doc, or PhD student.

Contact me and let’s work together.

A little biography

In 2013 I received my PhD in Chemistry from ENS Lyon, France, where I lived for over 3 years. After that I relocated to Sydney, Australia to work on two postdoctoral fellowships in chemical biology, molecular sensing and fluorescence microscopy. Now, I am back in Central Europe with my own research group and a global network of collaborators. I am passionate about interdisciplinary chemistry research, bringing together the global molecular imaging and chemical biology community, scientific outreach, and dissemination to the public. In my spare time I like running, playing football, learning about anthropology and travelling. I speak Polish, English, Russian and French.

My research

I lead the “Molecular Probes and Pro-drugs” Department, which performs cutting-edge research at the intersection of chemistry, cellular biology and molecular sensing. We perform design, synthesis and application of unique chemical tools to study the biochemistry and molecular interactions in cells and animals. Such tools include:

I am also the head of the Centre for High Throughput Screening Studies, where we provide expertise and infrastructure for identification, optimisation and validation of biologically-active small molecules.

  • dual analyte fluorescent probes
  • caged bioluminogenic substrates
  • probes for covalent protein labelling in cells

Read more on my research page.

Recent Publications

IJ Carney, JL Kolanowski, Z Lim, B Chekroun, TW Hambley, EJ New. A ratiometric iron probe enables investigation of iron distribution within tumour spheroids. Metallomics, 2018, 10, 553-556.

JL Kolanowski, F Liu, EJ New. Fluorescent probes for the simultaneous detection of multiple analytes in biology. Chemical Society Reviews, 2018, 47, 195-208.

JL Kolanowski, LJ Dawson, L Mitchell, Z Lim, ME Graziotto, WK Filipek, TW Hambley & EJ New.  A fluorescent probe for investigating metabolic stability of active transplatin analogues. Sensors and Actuators B: Chemical, 2018, 255, 2721-2724.

Current research grants:

SONATA

Caged bioluminogenic substrates for a selective molecular imaging of biochemical parameters in cancer (grant SONATA 13, nr UMO-2017/26/D/NZ1/01234), National Science Centre, 2018-2021

HOMING

MultiGATE: dual-analyte responsive fluorescent probes for a real-time multi-parametric sensing in cellular models, (grant Homing, nr: Homing/2017-4/33), Fundacja na rzecz Nauki Polskiej (FNP), 2018-2020

OPUS

Small Molecule tools to investigate local microenvironment of proteins (grant OPUS 15, nr UMO-2018/29/B/ST4/01498), National Science Centre, 2019-2022